Evolution of Breast Cancer Recurrence Risk Prediction: A Systematic Review of Statistical and Machine Learning-Based Models.

PURPOSE: Selection of appropriate adjuvant therapy to ultimately reduce the risk of breast cancer (BC) recurrence is a challenge for medical oncologists. Several automated risk prediction models have been developed using retrospective clinical data and have evolved significantly over the years in terms of predictors of recurrence, data usage, and predictive techniques (statistical/machine learning [ML]). METHODS: Following PRISMA guidelines, we performed a systematic literature review of the aforementioned statistical and ML models published between January 2008 and December 2022 through searching five digital databases-PubMed, ScienceDirect, Scopus, Cochrane, and Web of Science. The comprehensive search yielded a total of 163 papers and after a screening process focusing on papers that dealt exclusively with statistical/ML methods, only 23 papers were deemed appropriate for further analysis. We benchmarked the studies on the basis of development, evaluation metrics, and validation strategy with an added emphasis on racial diversity of patients included in the studies. RESULTS: In total, 30.4% of the included studies use statistical techniques, while 69.6% are ML-based. Among these, traditional ML models (support vector machines, decision tree, logistic regression, and naïve Bayes) are the most frequently used (26.1%) along with deep learning (26.1%). Deep learning and ensemble learning provide the most accurate predictions (AUC = 0.94 each). CONCLUSION: ML-based prediction models exhibit outstanding performance, yet their practical applicability might be hindered by limited interpretability and reduced generalization. Moreover, predictive models for BC recurrence often focus on limited variables related to tumor, treatment, molecular, and clinical features. Imbalanced classes and the lack of open-source data sets impede model development and validation. Furthermore, existing models predominantly overlook African and Middle Eastern populations, as they are trained and validated mainly on Caucasian and Asian patients.

Real-Time Infoveillance of Moroccan Social Media Users' Sentiments towards the COVID-19 Pandemic and Its Management.

The impact of COVID-19 on socio-economic fronts, public health related aspects and human interactions is undeniable. Amidst the social distancing protocols and the stay-at-home regulations imposed in several countries, citizens took to social media to cope with the emotional turmoil of the pandemic and respond to government issued regulations. In order to uncover the collective emotional response of Moroccan citizens to this pandemic and its effects, we use topic modeling to identify the most dominant COVID-19 related topics of interest amongst Moroccan social media users and sentiment/emotion analysis to gain insights into their reactions to various impactful events. The collected data consists of COVID-19 related comments posted on Twitter, Facebook and Youtube and on the websites of two popular online news outlets in Morocco (Hespress and Hibapress) throughout the year 2020. The comments are expressed in Moroccan Dialect (MD) or Modern Standard Arabic (MSA). To perform topic modeling and sentiment classification, we built a first Universal Language Model for the Moroccan Dialect (MD-ULM) using available corpora, which we have fine-tuned using our COVID-19 dataset. We show that our method significantly outperforms classical machine learning classification methods in Topic Modeling, Emotion Recognition and Polar Sentiment Analysis. To provide real-time infoveillance of these sentiments, we developed an online platform to automate the execution of the different processes, and in particular regular data collection. This platform is meant to be a decision-making assistance tool for COVID-19 mitigation and management in Morocco.

MoreAir: A Low-Cost Urban Air Pollution Monitoring System.

MoreAir is a low-cost and agile urban air pollution monitoring system. This paper describes the methodology used in the development of this system along with some preliminary data analysis results. A key feature of MoreAir is its innovative sensor deployment strategy which is based on mobile and nomadic sensors as well as on medical data collected at a children's hospital, used to identify urban areas of high prevalence of respiratory diseases. Another key feature is the use of machine learning to perform prediction. In this paper, Moroccan cities are taken as case studies. Using the agile deployment strategy of MoreAir, it is shown that in many Moroccan neighborhoods, road traffic has a smaller impact on the concentrations of particulate matters (PM) than other sources, such as public baths, public ovens, open-air street food vendors and thrift shops. A geographical information system has been developed to provide real-time information to the citizens about the air quality in different neighborhoods and thus raise awareness about urban pollution.